Top 8 Medical Device Manufacturers in South Dakota 2026

Avera Home Medical Equipment — Watertown

Watertown, South Dakota

Avera Home Medical Equipment — Watertown operates in Watertown, South Dakota, at 1508 4th Street NE. The source does not provide a founding year, ownership structure, or founder names for this location.

INANOVATE

Sioux Falls, South Dakota

Inanovate is based in Sioux Falls, South Dakota. The company develops and manufactures Lyme-ID, an FDA 510(k)-cleared blood test for Lyme disease.

Midwest Medical Service

Watertown, South Dakota

Midwest Medical Service operates from Watertown, South Dakota, as a family-owned medical supply and equipment company. The business has served the region for more than three decades, building its reputation on customer service and hands-on work.

Pharmco Industries Inc

Chamberlain, South Dakota

Pharmco Industries Inc operates from its headquarters in Chamberlain, South Dakota, with additional locations in Platte, Winner, and Kimball. The company is locally owned and operated, though its founding year and founders are not publicly disclosed.

Pivotal Health Solutions

Watertown, South Dakota

Pivotal Health Solutions is headquartered in Watertown, South Dakota. The company operates under multiple brand lines including PHS Chiropractic, Armedica, Custom Craftworks, Athletic Edge, PHS Medical, Rev.247, and Pivotal Printing.

Hypnos Medical Equipment operates from Sioux Falls, South Dakota. The company supplies continuous positive airway pressure (CPAP) and bilevel positive airway pressure (BiPAP) devices, along with advanced modalities such as ASV and AVAPS, sourced from national brands including ResMed and Respironics.

Performance Respiratory, Inc. is listed under Medical Device Manufacturers in Rapid City, South Dakota.

Monument Health Home+ Home Medical Equipment - Rapid City is listed under Medical Device Manufacturers in Rapid City, South Dakota.