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Pharmaceutical Manufacturers

Top 22 Pharmaceutical Manufacturers in North Carolina 2026

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FirmsLedger lists 22 pharmaceutical manufacturers headquartered in North Carolina. The largest clusters are in Durham (5), Holly Springs (3), Clayton (2) and Greenville (2), and the other 10 are in 9 more cities. Durham listings include MedPharm USA CTM & Commercial Production, KBI Biopharma - Durham, Merck - Durham and 2 others.

By specialty, North Carolina has sterile injectables & fill-finish (8), biologics manufacturing (8), oral solid dose (4), API manufacturing (3) and vaccine manufacturing (3) listings. Capabilities that more than one of them list include drug substance (4), contract manufacturing (3), sterile fill-finish (3) and biologics CDMO (2).

Compare 10 pharmaceutical manufacturers in North Carolina
CompanyCitySpecialtyPhoneWebsite
MedPharm USA CTM & Commercial ProductionDurhamFormulation Development(919) 549-9700medpharm.com
KBI Biopharma - DurhamDurhamMammalian cell line development(919) 479-9898kbibiopharma.com
Cambrex High PointHigh PointAPI Manufacturing—cambrex.com
Cosette Pharmaceuticals - LincolntonLincolntonSemi-Solids—cosettepharma.com
FUJIFILM Biotechnologies - Holly SpringsHolly SpringsBiologics CDMO—fujifilmbiotechnologies.fujifilm.com
Fresenius Kabi USA - WilsonWilsonPrefilled Syringes—fresenius-kabi.com
Grifols - ClaytonClaytonPlasma Fractionation—grifols.com
Sterling Pharma Solutions - CaryCarycGMP API manufacturing—sterlingpharmasolutions.com
Thermo Fisher Scientific Pharma Services - Greenville (Patheon)GreenvilleSterile Fill-Finish(252) 758-3436patheon.com
Merck - DurhamDurhamVaccine Manufacturing—merck.com

All Pharmaceutical in North Carolina

MedPharm USA CTM & Commercial Production

Durham, North Carolina

MedPharm was founded in 1999 at King’s College London, emerging from academic research into topical and transdermal drug delivery. The company established its U.S.

KBI Biopharma - Durham

Durham, North Carolina

KBI Biopharma operates a contract development and manufacturing organization (CDMO) focused on biologics from its Durham, North Carolina facility The company is a subsidiary of JSR Life Sciences and maintains additional sites in Research Triangle Park, Boulder, Louisville, The Woodlands, Geneva, and Leuven. While the firm celebrates 30 years of experience, an explicit founding year is not disclosed.

Cambrex High Point

High Point, North Carolina

Cambrex High Point operates in High Point, North Carolina, as a dedicated facility within Cambrex's global contract development and manufacturing network. The site focuses on small-molecule active pharmaceutical ingredient (API) development and manufacturing for Phase I through III clinical trials and small-volume commercial supply.

Cosette Pharmaceuticals - Lincolnton

Lincolnton, North Carolina

Cosette Pharmaceuticals operates a manufacturing hub in Lincolnton, North Carolina. The company traces its heritage back more than 100 years, building on a century-plus legacy in pharmaceutical production.

FUJIFILM Biotechnologies - Holly Springs

Holly Springs, North Carolina

FUJIFILM Biotechnologies operates a large-scale contract development and manufacturing organization (CDMO) site in Holly Springs, North Carolina. The facility is part of Fujifilm Corporation's global biologics network, which maintains additional production sites in the United States and Europe.

Fresenius Kabi USA - Wilson

Wilson, North Carolina

Fresenius Kabi USA operates a sterile fill-finish facility in Wilson, North Carolina. Ownership is corporate, with the Wilson plant serving as a key U.S.

Grifols - Clayton

Clayton, North Carolina

Grifols’ Clayton, North Carolina facility operates as a plasma fractionation complex housing a fractionation plant and an immunoglobulin purification and filling plant. The site is part of Grifols, a global healthcare company founded in 1909 by Dr.

Sterling Pharma Solutions - Cary

Cary, North Carolina

Sterling Pharma Solutions operates a cGMP active pharmaceutical ingredient (API) manufacturing facility in Cary, North Carolina. The site is part of Sterling Pharma Solutions Limited, a UK-registered company (registration 05712796) with a 50-plus-year heritage in small-molecule development and manufacturing.

API ManufacturingPharmaceutical ManufacturerscGMPISO/IEC 9001:2015ISO/IEC 27001

Thermo Fisher Scientific Pharma Services - Greenville (Patheon)

Greenville, North Carolina

Thermo Fisher Scientific Pharma Services operates a multipurpose pharmaceutical manufacturing campus in Greenville, North Carolina. The campus provides solid dose manufacturing and packaging alongside sterile liquid filling and lyophilization for small molecules and biologics.

Merck - Durham

Durham, North Carolina

Merck’s Durham, North Carolina site houses a 225,000-square-foot facility dedicated to vaccine manufacturing. The site operates as part of Merck & Co., Inc., a global biopharmaceutical company headquartered in Rahway, New Jersey, with a history spanning more than 130 years of developing medicines and vaccines.

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Frequently asked questions

Which pharmaceutical manufacturers in North Carolina list drug substance?

4 companies list it: FUJIFILM Biotechnologies - Holly Springs, Merck - Durham, Astellas Gene Therapies - Sanford and Biogen - Research Triangle Park.

Which certifications do pharmaceutical manufacturers in North Carolina list?

cGMP: KBI Biopharma - Durham, Cosette Pharmaceuticals - Lincolnton and 2 others. ISO 14001: Cambrex High Point, Fresenius Kabi USA - Wilson and Grifols - Clayton.

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