Grand River Aseptic Manufacturing

About Grand River Aseptic Manufacturing

The company does not disclose its founding year or ownership structure, but it presents itself as a contract development and manufacturing organization focused on sterile injectable fill-finish. GRAM runs five filling lines equipped with isolator technology, handling liquid and lyophilized vials, prefilled syringes, and cartridges. The site supports formulation volumes up to 1,000 liters and offers low- and high-speed filling, lyophilization with auto-loader, single-use and product-dedicated equipment, terminal sterilization, automated through manual inspection, labeling, packaging, serialization, aggregation, analytical testing, and regulatory support. Three of its five facilities are designed to meet revised EU GMP Annex 1 requirements. The CDMO serves pharmaceutical and biotechnology companies developing biologics, small molecules, and vaccines, from clinical trials through commercial supply. It also partners with drug-delivery device innovators to tailor fill-finish for autoinjectors and on-body delivery systems. GRAM emphasizes its team’s collaborative relationships and agility as differentiators, stating that clients consider its approach unique in the pharma industry. The company’s mission centers on delivering high-quality injectable solutions with reliability to advance patient care.

Equipment

• Groninger syringe and cartridge filling line
• Isolator technology
• Lyophilizer with auto-loader
• Single-use systems
• Product-dedicated process equipment

Company details

Location

Grand Rapids, Michigan

Company type

Contract manufacturer / job shop

Production volume

Low to high volume; formulation volumes up to 1,000 L

Certifications

EU GMP Annex 1

Listed under

• Medical Device Manufacturers in Michigan

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